Biopharma Processing
 
     
Biopharmaceuticals are pharmaceutical products that contain biotechnology derived proteins as active substances.

Over years a very large number of different biomolecules and their importance / role in various biochemical process have been researched upon which in turn has thrown up very many different types of biopharmaceutical products for various applications in the field of therapeutics and medical diagnostics.

These can be categorized into the following groups but are not limited to:
 

Biopharma Processing

 

  Recombinant Proteins
  Vaccines
  Plasma Fractionation Products
  Monoclonal Antibodies (mAbs)

The manufacturing processes for most of different biopharmaceuticals have the following major generic operations.

mdi offers a very wide range of microfiltration devices for for media preparation and clarification, bioburden reduction and sterilization of a variety of fluid streams in the upstream as well as downstream process areas.
 
 
 
  • Cell Culture & Fermentation
  • Harvesting and Clarification
  • Purification
  • Aseptic Fill & Finish

  Mammalian Cell Culture
   - Media Preparation 
   -  Sterile venting 

  Microbial Fermentation
  -  Sterile venting
  -  Sterile air sparging
  -  Sterile Filtration of growth regulators
  -  Sterile filtration of alkaline/acidic solutions for pH control 

      

  Harvesting and Clarification
   -  Mammalian Cell Culture Clarification
   -  Microbial Fermentation Broth Clarification


 
     Down Stream Processing
 
 
 
 

  Aseptic Fill and Finish
   -  Sterilization of buffer
   -  Sterilization of product
   -  Sterilization of air/gases
   -  Sterile venting
 
 
 


 
 
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  Biopharmaceuticals
  - Recombinant Proteins
  - Vacciness
  - Plasma Fractions
  - Monoclonal Antibodies

  Bioprocessing
 Cell Culture and  Fermentation
-  Mammalian Cell Culture
-  Microbial Fermentation
 Harvesting and Clarification
 Mammalian Cell Culture    Clarification
 Microbial Fermentation Broth    Clarification
 Downstream Processing
 Aseptic Fill and Finish

 
 
 
 
 
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