Monoclonal antibodies (mAbs) are monospecific antibodies that are identical as these are made by one type of immune cells that are all clones of a single parent cell.
mAbs can be produced against almost any given substance and as these are very specific to the substance, they are being used for detection (diagnostic) as well as treatment (therapeutic).
mAbs are being produced through Hybridoma Cell Production Technique using cell reactors. Another technology is recombinant antibody engineering which uses viruses or yeast to create antibodies in fermenters.
Diagnostic Applications
Biochemical analysis for diagnosis of pregnancy, cancers, humoral disorders, infectious diseases
Diagnostic Imaging for the detection of myocardial infarction, deep vein thrombosis, atherosclerosis, cancers, bacterial infections
Therapeutic Applications
Direct use as therapeutic agents for disease-causing organisms, treatment of cancers, for post organ transplant, immunosuppression treatment of AIDS, and autoimmune diseases
As targeting agents in the therapy as immune toxins (for treatment of cancers), in drug delivery, for dissolving blood clots, in radio-immunotherapy of tumors
For Microfiltration applications in mAb production phase refer to generic bioproduction processes (Click...)